Thermo Fisher Scientific Serotonin Transporter (SERT) (extracellular) Polyclonal Antibody

Thermo Fisher Scientific Serotonin Transporter (SERT) (extracellular) Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

• Reconstitution: Add 25 µL, 50 µL, or 0.2 mL double distilled water (DDW) depending on sample size.
• Ships as lyophilized powder at room temperature.
• Store at -20°C upon arrival.
• Reconstituted solution can be stored at 4°C (protected from light) for up to 1 week.
• For long-term storage, aliquot and store at -20°C.
• Avoid multiple freeze/thaw cycles.
• Centrifuge antibody preparations before use (10,000 × g, 5 min).

Target Information

Serotonin Transporter (SERT) is an integral membrane protein responsible for transporting serotonin from synaptic spaces into presynaptic neurons. It terminates serotonin action and recycles it in a sodium-dependent manner. SERT is a target of psychomotor stimulants such as amphetamines and cocaine and belongs to the sodium:neurotransmitter symporter family.
A repeat length polymorphism in its promoter region affects serotonin uptake rate and may be associated with sudden infant death syndrome, aggressive behavior in Alzheimer’s disease, and depression susceptibility under emotional stress.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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