Thermo Fisher Scientific Serotonin Transporter (SERT) (extracellular) Polyclonal Antibody
Serotonin Transporter(SERT) 단백질의 세포외 영역을 인식하는 rabbit polyclonal antibody. Western blot, IHC, ICC, Flow cytometry에 적합. 항원 친화 크로마토그래피로 정제되었으며, lyophilized 형태로 제공. 연구용으로만 사용 가능.
- 카탈로그번호
- AMT-004-xxxxx (3개 옵션)
- 판매단위
- pk
카탈로그
3개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Serotonin Transporter (SERT) (extracellular) Polyclonal Antibody
Thermo Fisher Scientific Serotonin Transporter (SERT) (extracellular) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:400 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 2.5 µg |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)EMRNEDVSEVAKD, corresponding to amino acid residues 388–400 of rat SERT, extracellular loop |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitution: Add 25 µL, 50 µL, or 0.2 mL double distilled water (DDW) depending on sample size.
- Ships as lyophilized powder at room temperature.
- Store at -20°C upon arrival.
- Reconstituted solution can be stored at 4°C (protected from light) for up to 1 week.
- For long-term storage, aliquot and store at -20°C.
- Avoid multiple freeze/thaw cycles.
- Centrifuge antibody preparations before use (10,000 × g, 5 min).
Target Information
Serotonin Transporter (SERT) is an integral membrane protein responsible for transporting serotonin from synaptic spaces into presynaptic neurons. It terminates serotonin action and recycles it in a sodium-dependent manner. SERT is a target of psychomotor stimulants such as amphetamines and cocaine and belongs to the sodium:neurotransmitter symporter family.
A repeat length polymorphism in its promoter region affects serotonin uptake rate and may be associated with sudden infant death syndrome, aggressive behavior in Alzheimer’s disease, and depression susceptibility under emotional stress.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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