Thermo Fisher Scientific CD147/EMMPRIN/Neurothelin Monoclonal Antibody (BSG/7949)
CD147/EMMPRIN/Neurothelin 단클론 항체로 인간 시료에 반응하며, IHC 및 Peptide Array에 사용 가능. 단백질 A/G로 정제된 액상 형태이며, 4°C에서 보관. 세포 표면 CD147 연구 및 종양 진행 관련 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 2 µg/mL |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 0.5–1 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | BSG/7949 |
| Immunogen | Recombinant full-length human BSG protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD147 (also known as basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF, tumour cell-derived collagenase-stimulatory factor) is a 50–60 kDa glycoprotein with multiple glycosylated forms.
It is a plasma membrane protein involved in:
- Spermatogenesis
- Embryo implantation
- Neural network formation
- Tumor progression
CD147 is a member of the immunoglobulin superfamily and is highly expressed in metabolically active cells such as lymphoblasts, inflammatory cells, brown adipocytes, and malignant tumor cells.
It facilitates cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulates integrin functions, and plays roles in cell development, activation, fetal development, and retinal function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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