Thermo Fisher Scientific Daple Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

Immunoprecipitation (IP)

2-5 µg/mg lysate

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Region between residue 1450 and 1500 of human Dvl-Associating Protein with a High Frequency of Leucine Residues. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CCDC88C,uniProtId:Q9P219-1,ncbiNodeId:9606,antigenRange:1450-1500,antigenLength:2028,antigenImageFileName:A302-951A_CCDC88C_Q9P219-1_Rabbit.svg,antigenImageFileNamePDP:A302-951A_CCDC88C_Q9P219-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

phosphate/tris citrate, pH 7-8

Contains

0.09% sodium azide

Storage conditions

4° C

Shipping conditions

Wet ice

Product Specific Information

The recommended shelf life for this product is 1 year from date of receipt.

Target Information

This gene encodes a ubiquitously expressed coiled-coil domain-containing protein that interacts with the disheveled protein and is a negative regulator of the Wnt signaling pathway. The protein encoded by this gene has a PDZ-domain binding motif in its C-terminus with which it interacts with the disheveled protein. Disheveled is a scaffold protein involved in the regulation of the Wnt signaling pathway. The Wnt signaling pathway plays an important role in embryonic development, tissue maintenance, and cancer progression. Mutations in this gene cause autosomal recessive, primary non-syndromic congenital hydrocephalus; a condition characterized by excessive accumulation of cerebrospinal fluid in the ventricles of the brain.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.