Thermo Fisher Scientific Daple Polyclonal Antibody
Daple 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 인간 시료에 반응하며 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 4°C 보관하며 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Assay-dependent
Immunoprecipitation (IP)
- 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1450 and 1500 of human Dvl-Associating Protein with a High Frequency of Leucine Residues |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
This gene encodes a ubiquitously expressed coiled-coil domain-containing protein that interacts with the disheveled protein and acts as a negative regulator of the Wnt signaling pathway.
The encoded protein has a PDZ-domain binding motif in its C-terminus, allowing interaction with the disheveled protein.
Disheveled functions as a scaffold protein in Wnt pathway regulation, which is critical for embryonic development, tissue maintenance, and cancer progression.
Mutations in this gene cause autosomal recessive, primary non-syndromic congenital hydrocephalus, characterized by excessive accumulation of cerebrospinal fluid in the brain ventricles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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