Thermo Fisher Scientific PGRMC2 Polyclonal Antibody
PGRMC2 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 Immunoprecipitation에 적합합니다. 0.2 mg/mL 농도의 액상 형태이며, 4°C에서 보관합니다. 인간 PGRMC2의 173-223 잔기 영역을 면역원으로 사용하였습니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 173 and 223 of human Progesterone Receptor Membrane Component 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
PGRMC2 (progesterone receptor membrane component 2), also known as DG6 (steroid receptor protein DG6) or PMBP (progesterone membrane-binding protein), is a single-pass membrane protein belonging to the cytochrome b5 family (MAPR subfamily). Expressed in sperm, PGRMC2 is believed to function as a steroid receptor and may participate in the progesterone-dependent sperm acrosome reaction. PGRMC2 shares approximately 50% overall sequence identity with its close relative PGRMC1. Loss of the gene encoding PGRMC2 is associated with metastasis in uterine endocervical adenocarcinomas, suggesting a potential role in suppression of metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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