Thermo Fisher Scientific TLN1 Monoclonal Antibody (5C1)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

3 µg/mL

-

ELISA (ELISA)

0.03 ng/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG3, kappa

Class

Monoclonal

Type

Antibody

Clone

5C1

Immunogen

TLN1 (NP_006280, 1052 a.a. approximately 1149 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Talin 1,uniProtId:Q9Y490-1,ncbiNodeId:9606,antigenRange:1052-1149,antigenLength:2541,antigenImageFileName:H00007094-M05_Talin_1_Q9Y490-1_House_mouse.svg,antigenImageFileNamePDP:H00007094-M05_Talin_1_Q9Y490-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: SALSVVQNLE KDLQEVKAAA RDGKLKPLPG ETMEKCTQDL GNSTKAVSSA IAQLLGEVAQ GNENYAGIAA RDVAGGLRSL AQAARGVAAL TSDPAVQA

Target Information

Talin, a multifunctional constituent of cell-substratum attachment sites, is a high molecular weight protein (225-235 kDa) found in variety of tissues and cell types. It is localized at a subset of adherens junctions, specialized cell-cell and cell-matrix associations that are characterized by the presence of filamentous actin at the cytoplasmic face of the junctional complex. In cultured cells, talin is absent from cell-cell junctions and found predominantly at adhesion plaques and in fibrillar streaks underlying cell surface fibronectin. Talin interacts with at least two other proteins that are localized at adhesion plaques, vinculin and integrin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.