Thermo Fisher Scientific TK1 Monoclonal Antibody (3F9)
Human TK1 단백질을 인식하는 Mouse monoclonal antibody (Clone 3F9). Western blot 및 ELISA에 적합. Affinity chromatography로 정제된 액상 형태이며, PBS(pH 7.4) buffer에 보존제 없이 제공. 연구용으로 세포 분열 관련 단백질 분석에 활용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 1 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3F9 |
| Immunogen | TK1 (AAH07986.1, 1–234 a.a) full-length recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
MSCINLPTVL PGSPSKTRGQ IQVILGPMFS GKSTELMRRV RRFQIAQYKC LVIKYAKDTR YSSSFCTHDR NTMEALPACL LRDVAQEALG VAVIGIDEGQ FFPDIVEFCE AMANAGKTVI VAALDGTFQR KPFGAILNLV PLAESVVKLT AVCMECFREA AYTKRLGTEK EVEVIGGADK YHSVCRLCYF KKASGQPAGP DNKENCPVPG KPGEAVAARK LFAPQQILQC SPAN
Target Information
Thymidine Kinase (TK1) is a highly conserved phosphotransferase present in most living cells. It catalyzes the reaction:
deoxythymidine + ATP → deoxythymidine 5'-phosphate + ADP
TK1 is essential for DNA synthesis and is involved in the mechanism of action of many antiviral drugs such as azidothymidine (AZT). It is also used in the selection of hybridoma cell lines for monoclonal antibody production. TK1 expression correlates with cell proliferation and has numerous research and clinical applications.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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