Thermo Fisher Scientific Notch1 Monoclonal Antibody (OTI3E12), TrueMAB
Human Notch1 단백질을 인식하는 Mouse monoclonal antibody로, Western blot, IHC, ICC/IF 등 다양한 응용에 적합합니다. TrueMAB 포맷으로 높은 특이성과 재현성을 제공하며, 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 | - |
| Immunocytochemistry (ICC/IF) | 1:50 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3E12 |
| Immunogen | Recombinant protein expressed in E. coli corresponding to amino acids 2300–2556 of human NOTCH1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The Notch gene family encodes transmembrane proteins with multiple cysteine-rich EGF-like repeats in the extracellular region. Four Notch genes (Notch1, Notch2, Notch3, and Notch4/Int-3) are known in mammals and play roles in the differentiation of the nervous system and other structures.
EGF-like proteins Delta and Serrate act as ligands for Notch1. Mature Notch proteins are heterodimeric receptors formed by cleavage of Notch pre-proteins into an extracellular subunit (NEC) and a transmembrane subunit (Ntm).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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