Thermo Fisher Scientific TRF2 Polyclonal Antibody
TRF2 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간, 마우스, 랫트 반응성. Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합. Protein A로 정제된 고순도 항체로 안정적인 액상 형태 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human TRF2, amino acids 301–400 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TRF2 is a ubiquitously expressed protein involved in the control of telomere length. It contains a Myb-related DNA binding motif and binds to duplex TTAGGG repeats, localizing to all human telomeres in metaphase chromosomes. TRF2 helps protect chromosome ends by maintaining the correct telomere structure. Mutant forms of TRF2 have been shown to prevent senescence in primary human cells, and inhibition of TRF2 can induce apoptosis in certain mammalian cell types.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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