Thermo Fisher Scientific Interferon alpha-2 Monoclonal Antibody (KT5)
인간 IFN-alpha2a 및 IFN-alpha2b를 모두 인식하는 단클론 항체. Western blot에 최적화됨. 마우스 IgG1 아이소타입, Protein A 정제, 액상 형태. 2–8°C 보관, 장기 보관 시 -20°C 권장. 연구용으로만 사용.
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Applications
- Western Blot (WB): 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KT5 |
| Immunogen | Recombinant IFN-alpha2a |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 1 month. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2122495 |
Product Specific Information
This antibody reacts with both IFN alpha 2a and IFN alpha 2b.
Target Information
Interferon alpha (IFN-alpha) is a Type I interferon that belongs to a family of structurally related, species-specific proteins found only in vertebrates. Interaction of IFN-alpha with its receptor activates several signaling pathways involved in innate immune responses against viral infections. In humans, the IFN-alpha gene is located on chromosome 9 and includes 14 alpha isoforms, as well as beta, omega, epsilon, and kappa isoforms. Homologous molecules exist across many species, including mammals, birds, reptiles, and fish. IFN-alpha is primarily produced by plasmacytoid dendritic cells and plays a critical role in antiviral defense and modulation of adaptive immunity. Dysregulation of IFN-alpha is associated with diseases such as Hepatitis C and Hepatitis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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