Thermo Fisher Scientific Synaptotagmin 1/2 Polyclonal Antibody
Synaptotagmin 1/2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. Protein A 정제, 1 mg/mL 농도, -20°C 보관. 신경전달물질 분비 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human synaptotagmin-2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Synaptotagmins are a large gene family of synaptic vesicle type III integral membrane proteins that regulate both exocytosis and endocytosis, playing a crucial role in neurotransmitter secretion.
Calcium binding to Synaptotagmin I triggers neurotransmitter release at the synapse.
Synaptotagmin II is phosphorylated by WNK1, regulating calcium-dependent interactions.
Synaptotagmin III mediates calcium-dependent exocytosis in endocrine cells and neurons.
Synaptotagmin IV is expressed in neuronal tissues with the highest mRNA levels in the hippocampus.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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