Thermo Fisher Scientific IL-6 Receptor Monoclonal Antibody (255820)
Thermo Fisher Scientific의 IL-6 Receptor Monoclonal Antibody (Clone 255820)은 마우스 IL-6 수용체를 인식하는 Rat IgG1 단일클론 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 단백질 A/G로 정제되었으며, PBS와 trehalose로 보존되어 안정적입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunocytochemistry (ICC/IF) | 8–25 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 255820 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant mouse IL-6 R alpha (Leu20–Glu357) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609192 |
Product Specific Information
- No cross-reactivity with recombinant human IL-6 R in direct ELISAs and Western blots.
- Reconstitute at 0.5 mg/mL in sterile PBS.
- Endotoxin level <0.10 EU per 1 µg of antibody (LAL method).
Target Information
Interleukin 6 receptor (IL6R), also known as CD126, is a type I cytokine receptor that forms part of the IL-6 receptor complex. It regulates cell growth, differentiation, and immune response. The receptor consists of IL6R and IL6 signal transducer (IL6ST/GP130). Dysregulated IL6/IL6R signaling is associated with diseases such as multiple myeloma, autoimmune disorders, and prostate cancer. Alternative splicing variants and a pseudogene on chromosome 9 have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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