Thermo Fisher Scientific CTHRC1 Polyclonal Antibody
CTHRC1 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC, Flow Cytometry 등 다양한 응용에 적합. 고순도 Protein A 및 항원 친화 크로마토그래피 정제. 인간 시료 반응성, 연구용 전용.
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Thermo Fisher Scientific CTHRC1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:16,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 | - |
| Flow Cytometry (Flow) | 1:10–1:50 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide between 19–46 amino acids from the N-terminal region of human CTHRC1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2635092 |
Target Information
The Collagen triple helix repeat-containing protein (CTHRC1) is a glycosylated, secreted protein transiently expressed in the arterial wall in response to injury. It contributes to vascular remodeling by inhibiting collagen expression and deposition and promoting cell migration.
CTHRC1 is highly expressed in multiple human cancers, including pancreatic cancer, where it plays a role in progression and metastasis by regulating tumor cell migration and adhesion.
Overexpression of CTHRC1 can serve as an independent prognostic marker in gastric cancer. Mutations at this locus have been associated with Barrett esophagus and esophageal adenocarcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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