Thermo Fisher Scientific Insulin Polyclonal Antibody
Western blot, IHC, ELISA, IP 등 다양한 응용에 사용 가능한 인슐린 폴리클로날 항체. 사람, 생쥐, 돼지, 쥐 반응성. Protein A 정제, 1 mg/mL 농도의 액상 형태. -20°C 보관, 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| ELISA | 1:500–1:1,000 |
| Immunoprecipitation (IP) | 1–2 µg |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Pig, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated Insulin from porcine pancreas |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein, and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Insulin is a 51-amino acid polypeptide produced from a precursor peptide, proinsulin, which is post-translationally cleaved into two chains (peptide A and peptide B) linked via two disulfide bonds and one molecule of C-peptide. Insulin deficiency results in diabetes mellitus, one of the leading causes of morbidity and mortality. Insulin is also present in tumors of β-cell origin such as insulinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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