Thermo Fisher Scientific ACBD3 Monoclonal Antibody (OTI3A1), TrueMAB
ACBD3 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot, IHC(P), Flow Cytometry에 적합. Human, Dog, Rat 시료에 반응하며, 고순도 Affinity Chromatography 정제. PBS/BSA/glycerol 완충액에 보관되며 -20°C에서 안정적으로 유지.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3A1 |
| Immunogen | Full-length human recombinant ACBD3 protein produced in HKE293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
GOLPH1 (also known as GCP60) is a Golgi protein that interacts with the integral membrane protein giantin and contributes to maintaining Golgi structure. It also interacts with Golgin-160, which can be cleaved by caspases-2, -3, and -7, leading to nuclear localization of Golgin-160 fragments. The interaction between GOLPH1 and cleaved Golgin-160 fragments is regulated by the oxidation state of Cys-463 within GOLPH1. Additionally, GOLPH1 interacts with Numb, a cytosolic signaling protein involved in asymmetric cell division of neural progenitor cells, suggesting that Golgi fragmentation and reconstitution during the cell cycle may regulate Numb signaling and link cell fate with cell cycle progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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