Thermo Fisher Scientific DOK7 Monoclonal Antibody (OTI3C12), TrueMAB
DOK7 단백질을 인식하는 Mouse monoclonal antibody로 Western blot 및 Flow cytometry에 적합. Affinity chromatography로 정제된 액상 형태이며, PBS/BSA/glycerol buffer에 보관. 신경근 시냅스 형성과 관련된 연구용으로 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3C12 |
| Immunogen | Full length human recombinant protein of human DOK7 produced in HEK293T cell. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is essential for neuromuscular synaptogenesis. It functions in aneural activation of muscle-specific receptor kinase, required for postsynaptic differentiation and clustering of the acetylcholine receptor in myotubes. This protein can induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene cause familial limb-girdle myasthenia autosomal recessive (congenital myasthenic syndrome type 1B). Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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