Thermo Fisher Scientific KIAA0020 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human KIAA0020. Recombinant protein control fragment (Product #RP-101853). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:KIAA0020,uniProtId:Q15397-1,ncbiNodeId:9606,antigenRange:496-639,antigenLength:648,antigenImageFileName:PA5-51704_KIAA0020_Q15397-1_Rabbit.svg,antigenImageFileNamePDP:PA5-51704_KIAA0020_Q15397-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2642992

Product Specific Information

Immunogen sequence: EHAQEVVLDK SACVLVSDIL GSATGDVQPT MNAIASLAAT GLHPGGKDGE LHIAEHPAGH LVLKWLIEQD KKMKENGREG CFAKTLVEHV GMKNLKSWAS VNRGAIILSS LLQSCDLEVA NKVKAALKSL IPTLEKTKST SKGI

Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 85%.

Target Information

Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress. Binds to double-stranded RNA or DNA without sequence specificity. Involved in development of the eye and of primordial germ cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.