ELK Biotechnology LT4R1 rabbit pAb
LT4R1 단백질을 인식하는 토끼 폴리클로날 항체로 WB 및 ELISA에 적합합니다. 인간, 마우스, 랫트 시료에서 반응하며, 세포막 단백질 검출에 활용됩니다. -20°C에서 1년 보관 가능하며, 1 mg/ml 농도로 제공됩니다.
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제품명
LT4R1 rabbit pAb
제품 개요
LT4R1 단백질을 인식하는 토끼 폴리클로날 항체로, Western Blot(WB) 및 ELISA 분석에 적합합니다. 인간, 마우스, 랫트 시료에서 반응하며 세포막 단백질 검출에 유용합니다.
제품 사양
| 항목 | 내용 |
|---|---|
| Applications | WB; ELISA |
| Recommended Dilutions | WB: 1:500–1:2000, ELISA: 1:5000–1:20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 38 kD |
| Gene ID (Human) | 1241 |
| Human Swiss-Prot No. | Q15722 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein |
| Species Reactivity | Human; Mouse; Rat |
Background
Function: Receptor for extracellular ATP, UTP, and ADP. The activity of this receptor is mediated by G proteins that activate a phosphatidylinositol-calcium second messenger system. It may function as the cardiac P2Y receptor involved in regulating cardiac muscle contraction through modulation of L-type calcium currents.
Receptor Function: Acts as a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
Post-translational Modification (PTM): Phosphorylated by GRK6 upon leukotriene B4 binding, promoting desensitization.
Similarity: Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity: Expressed at highest levels in heart and skeletal muscle, and at lower levels in brain and liver. High expression observed in lymphoid tissues.
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