Thermo Fisher Scientific AADAT Polyclonal Antibody
Thermo Fisher Scientific의 AADAT Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하는 Rabbit IgG 기반 항체입니다. Western blot, IHC, ICC/IF, ELISA에 사용 가능하며, 높은 특이성과 재현성을 제공합니다. 액상 형태로 보관이 용이하며 -20°C에서 안정적으로 저장됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:4,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 34–429 of human AADAT (NP_0012736111) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.38 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805265 |
Product Specific Information
Immunogen sequence:
PKSMISLAGG LPNPNMFPFK TAVITVENGK TIQFGEEMMK RALQYSPSAG IPELLSWLKQ LQIKLHNPPT IHYPPSQGQM DLCVTSGSQQ GLCKVFEMII NPGDNVLLDE PAYSGTLQSL HPLGCNIINV ASDESGIVPD SLRDILSRWK PEDAKNPQKN TPKFLYTVPN GNNPTGNSLT SERKKEIYEL ARKYDFLIIE DDPYYFLQFN KFRVPTFLSM DVDGRVIRAD SFSKIISSGL RIGFLTGPKP LIERVILHIQ VSTLHPSTFN QLMISQLLHE WGEEGFMAHV DRVIDFYSNQ KDAILAAADK WLTGLAEWHV PAAGMFLWIK VKGINDVKEL IEEKAVKMGV LMLPGNAFYV DSSAPSPYLR ASFSSASPEQ MDVAFQVLAQ LIKESL
Positive Samples: Mouse liver, Rat kidney
Cellular Location: Mitochondrion
Target Information
AADAT encodes a protein similar to mouse and rat kynurenine aminotransferase II. The rat protein functions as a homodimer with dual transaminase activities:
- Transamination of alpha-aminoadipic acid, the final step in the saccharopine pathway for L-lysine catabolism.
- Transamination of kynurenine to produce kynurenic acid, a neuroprotective compound.
Two alternative transcripts encoding the same isoform have been identified, though additional transcripts and isoforms may exist.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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