Thermo Fisher Scientific WHSC2 Polyclonal Antibody
WHSC2(NELFA) 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며, 인간 및 생쥐 시료에 반응. 고순도(affinity chromatography) 정제, 1 mg/mL 농도, PBS/glycerol buffer 보존. 연구용 전용.
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- PA5104336
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Thermo Fisher Scientific WHSC2 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NELFA (Accession Q9H3P2), corresponding to amino acid residues T328–N378 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | −20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2853646 |
Product Specific Information
Antibody detects endogenous levels of total NELF-A.
Target Information
This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein.
Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region and may play a role in the phenotype of WHS or Pitt-Rogers-Danks syndrome.
The encoded protein can react with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting potential use in specific immunotherapy for various cancer patients.
This protein is a member of the NELF (negative elongation factor) complex that regulates RNA polymerase II transcription elongation.
Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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