Thermo Fisher Scientific Human PON1 Recombinant Protein
인간 PON1 재조합 단백질로, E. coli 발현 시스템에서 생산된 고순도 단백질입니다. 웨스턴 블롯 등 다양한 면역학적 분석에서 양성 대조군으로 사용 가능합니다. N말단 His-tag 부착, 95% 이상 순도, -20°C 보관.
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Applications
- Western Blot (WB): Assay-dependent
- Control (Ctrl): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | E. coli |
| Amino Acid Sequence | Amino acids Met1–Leu355 containing an N-terminal His-tag |
| Tag | His-tag |
| Molecular Weight | 44.26 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | >95%, by SDS-PAGE under reducing conditions |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.69 mg/mL |
| Purification | Purified |
| Storage Buffer | 20 mM Tris-HCl, pH 8, with 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Product Specific Information
This product contains purified recombinant human Paraoxonase 1 (PON1) protein with an N-terminal hexahistidine tag.
It may be used as a positive control in various immunological assays.
Target Information
The paraoxonase (PON) gene family in humans has three members: PON1, PON2, and PON3, located on chromosome 7q21.3–22.1.
PON1 is primarily synthesized in the liver and secreted into plasma, where it associates with high-density lipoproteins (HDL).
It hydrolyzes active metabolites of several organophosphorus insecticides (e.g., chlorpyrifos oxon, diazoxon) and nerve agents such as sarin, soman, and VX.
PON1 polymorphism is associated with neurodegeneration and may be an independent risk factor for Parkinson’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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