Thermo Fisher Scientific Phospho-LKB1 (Ser334) Polyclonal Antibody
인간 LKB1 단백질의 Ser334 인산화 부위를 인식하는 폴리클로날 항체. 면역조직화학(IHC) 등 연구용으로 사용 가능. 액상 형태, 1 mg/mL 농도, -20°C 보관. 종양 억제 단백질 LKB1 관련 연구에 적합.
- 판매단위
- pk
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Thermo Fisher Scientific Phospho-LKB1 (Ser334) Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution
- 1:50–1:100
Publications
- [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human LKB1 around the phosphorylation site of Ser334 (W-R-SP-M-T) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2556293 |
Target Information
LKB1 (also known as STK11 - Serine/threonine-protein kinase STK11) is a member of the serine/threonine kinase family and functions as a tumor suppressor.
It physically associates with p53 and regulates specific p53-dependent apoptosis pathways.
LKB1 is found in both cytoplasm and nucleus and translocates to mitochondria during apoptosis.
It acts as a master upstream kinase regulating AMPK and AMPK-related kinases.
Mutations in the LKB1 gene are associated with Peutz-Jeghers syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-39742_LKB1_Q15831-1_Rabbit.svg, PA5-39742_LKB1_Q15831-1_Rabbit_PDP.jpeg)
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