Thermo Fisher Scientific Cathepsin K Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human Cathepsin K. Recombinant protein control fragment (Product #RP-106279). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Cathepsin K,uniProtId:P43235-1,ncbiNodeId:9606,antigenRange:279-326,antigenLength:329,antigenImageFileName:PA5-65613_Cathepsin_K_P43235-1_Rabbit.svg,antigenImageFileNamePDP:PA5-65613_Cathepsin_K_P43235-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2662871

Product Specific Information

Immunogen sequence: LAVGYGIQKGN KHWIIKNSWG ENWGNKGYIL MARNKNNACG IANLASF

Highest antigen sequence identity to the following orthologs - mouse 83%, rat 85%.

Target Information

The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.