Thermo Fisher Scientific Cathepsin K Polyclonal Antibody
Cathepsin K 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간 시료에 반응합니다. ICC/IF 분석에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol buffer에 보관되며, 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA565613
- 판매단위
- pk
카탈로그
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human Cathepsin K. Recombinant protein control fragment (Product #RP-106279) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2662871 |
Product Specific Information
Immunogen sequence:
LAVGYGIQKGN KHWIIKNSWG ENWGNKGYIL MARNKNNACG IANLASF
Highest antigen sequence identity to the following orthologs:
- Mouse: 83%
- Rat: 85%
Target Information
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. It belongs to the peptidase C1 protein family and is predominantly expressed in osteoclasts. Additionally, it is expressed in a significant fraction of human breast cancers, potentially contributing to tumor invasiveness. Mutations in this gene cause pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may also be subject to RNA editing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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