
Thermo Fisher Scientific ABC2 Polyclonal Antibody
Rabbit polyclonal antibody recognizing C17orf71 (ABC2) protein. Suitable for IHC applications at 1:100–1:500 dilution. Liquid form, unconjugated, 0.25 mg/mL concentration. Stable for 1 year at 4°C, shipped on wet ice. For research use only.
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Applications
- Immunohistochemistry (IHC)
Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Between amino acids 250–300 of C17orf71 (UniProt ID: Q8ND04-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Predicted reactivity (based on 100% sequence identity): Bovine, Horse, Rabbit, Pig, Orangutan, Monkey, Gorilla, Chimpanzee, Northern white-cheeked gibbon, Little brown bat
Target Information
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex). Required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: IHC-00555_C17orf71_Q8ND04-1_Rabbit_PDP.jpeg)
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