Thermo Fisher Scientific TBLR1 Recombinant Rabbit Monoclonal Antibody (23GB4935)
TBLR1 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 유세포분석에 적합합니다. HEK293F 발현 시스템에서 생산되었으며, 친화 크로마토그래피로 정제되었습니다. 인간, 생쥐, 랫트 시료에 반응하며, PBS/glycerol 완충액에 보관됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Flow Cytometry (Flow) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB4935 |
| Immunogen | A synthesized peptide derived from human TBLR1 (430–500AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Chromatin organization plays a fundamental role in regulating transcription in eukaryotic cells. The nuclear receptor corepressor (N-CoR) and silencing mediator of retinoid and thyroid hormone receptors (SMRT) participate in diverse transcriptional repression pathways. N-CoR and SMRT exist in large protein complexes and mediate repression by recruiting histone deacetylases to form repressive chromatin.
HDAC3 is the main HDAC associated with N-CoR and SMRT complexes and is essential for repression.
TBLR1, a WD-40 repeat protein, also associates with these complexes and is considered a core component, though its precise role remains to be elucidated.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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