Thermo Fisher Scientific MSH6 Recombinant Rabbit Monoclonal Antibody (021)
Human MSH6/GTBP 인식용 재조합 토끼 단클론 항체로, 높은 특이성과 민감도를 제공하며 로트 간 일관성이 우수합니다. WB, IHC, ICC/IF 등 다양한 응용에 적합하며, 방부제 무첨가 포뮬레이션으로 연구용에 최적화되어 있습니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:20–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 021 |
| Immunogen | Synthetic peptide corresponding to the center region of Human MSH6/GTBP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785292 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
This antibody has specificity for Human MSH6/GTBP.
Target Information
The DNA mismatch repair MSH2/MSH6 heterodimer detects DNA damage and may promote apoptosis in normal cells, thereby protecting mammals from ultraviolet-induced malignant transformation and contributing to skin cancer prevention.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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