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Thermo Fisher Scientific Ruplizumab Chimeric Recombinant Rabbit Monoclonal Antibody (hu5c8 (Ruplizumab))
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CD40L에 특이적으로 결합하는 재조합 토끼 단일클론 항체로, Western blot, Flow cytometry, Inhibition assay에 사용 가능. HEK293 세포에서 발현되며 Protein A로 정제됨. 연구용으로 면역억제 관련 연구에 적합.
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마지막 업데이트 2025. 08. 05. 오전 02:10
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Thermo Fisher Scientific MA547966 Ruplizumab Chimeric Recombinant Rabbit Monoclonal Antibody (hu5c8 (Ruplizumab)) 200 ug pk판매 단위 pk ·
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696,000원VAT 포함 765,600원
Thermo Fisher Scientific · Thermo Fisher Scientific Ruplizumab Chimeric Recombinant Rabbit Monoclonal Antibody (hu5c8 (Ruplizumab))
Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | Assay-dependent | |
| Flow Cytometry (Flow) | 1 µg/mL | |
| Inhibition Assays (IA) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | hu5c8 (Ruplizumab) |
| Immunogen | Human CD40L |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074410 |
Product Specific Information
- Specificity: The antibody binds to CD40L with an IC50 of 0.845 µg/mL.
Target Information
Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive pharmaceutical and is a component of Antova.
It is an anti-CD40L monoclonal antibody. The binding of CD40 to its ligand, CD40L, is a critical element in T cell activation.
In systemic lupus erythematosus, CD40L is over-expressed on T cells, B cells, and monocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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