Thermo Fisher Scientific ADAMTS4 Polyclonal Antibody
ADAMTS4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체입니다. Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합하며, 인간·생쥐·랫트 시료에 반응합니다. Protein A로 정제된 액상 항체로 -20°C에서 보관합니다.
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Thermo Fisher Scientific ADAMTS4 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human ADAMTS4 (amino acids 501–839) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a member of the ADAMTS protein family. Members of this family share distinct protein modules, including a propeptide region, metalloproteinase domain, disintegrin-like domain, and thrombospondin type 1 motif. Individual members differ in the number of C-terminal TS motifs, and some have unique C-terminal domains.
The enzyme encoded by this gene lacks a C-terminal TS motif and is responsible for the degradation of aggrecan (a major cartilage proteoglycan) and brevican (a brain-specific extracellular matrix protein). This activity suggests roles in arthritic disease and in the central nervous system, potentially in glioma progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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