Thermo Fisher Scientific SGPL1 Polyclonal Antibody
인간, 생쥐, 랫트 반응성을 가진 SGPL1 폴리클로날 항체로 다양한 면역분석(IHC, ICC, Flow, ELISA)에 사용 가능. KLH 결합 합성 펩타이드(aa 301–400)로 면역화된 Rabbit IgG 항체. 고순도 Protein A 정제, 액상 형태로 -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human SGPL1 (amino acids 301–400) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Sphingosine-1-phosphate lyase cleaves phosphorylated sphingoid bases, such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. It elevates stress-induced ceramide production and apoptosis. The enzyme converts sphingosine-1-phosphate to phosphoethanolamine and palmitaldehyde using pyridoxal phosphate as a co-factor.
This type III membrane protein is found in the endoplasmic reticulum and is primarily expressed in the liver and kidney. It belongs to the group II decarboxylase family.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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