Thermo Fisher Scientific Galanin Chimeric Recombinant Mouse Monoclonal Antibody (4B3)
Galanin을 인식하는 마우스 단클론 항체로 높은 결합 친화도(Kd 0.07 nM)를 가짐. Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합. HEK293 세포에서 발현된 recombinant IgG1, kappa 형식. 단백질 A로 정제된 액상 형태로 제공.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 3 µg/mL |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| ELISA | Assay-dependent |
| Inhibition Assays (IA) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 4B3 |
| Immunogen | C-terminal fusions of KLH to human galanin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074435 |
Product Specific Information
Specificity: The antibody binds to galanin with an affinity constant (Kd) of 0.07 nM reported for the original antibody.
Target Information
Galanin is an endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiological functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release, and adrenal secretion. [Uniprot]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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