Thermo Fisher Scientific CD147 Recombinant Mouse Monoclonal Antibody (Ab-1)
CD147 단백질을 표적하는 Thermo Fisher의 재조합 마우스 단일클론 항체. ICC/IF, ELISA, 억제 분석 등 다양한 응용에 적합. HEK293 세포에서 발현된 IgG1 아이소타입 항체로, 4 nM 친화도를 보임. 단백질 A로 정제되어 높은 특이성과 재현성을 제공.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Immunocytochemistry (ICC/IF) | 10 µg/mL | |
| ELISA | Assay-dependent | |
| Inhibition Assays (IA) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | Ab-1 |
| Immunogen | Recombinant ectodomains of human basigin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074436 |
Product Specific Information
Specificity: The antibody binds to basigin with an affinity (Kd) of 4 nM reported for the original antibody.
Target Information
CD147 (also known as basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF, tumour cell-derived collagenase-stimulatory factor) is a 50–60 kDa glycoprotein with multiple glycosylated forms.
It is a plasma membrane protein important in spermatogenesis, embryo implantation, neural network formation, and tumor progression.
CD147 belongs to the immunoglobulin superfamily and is highly expressed in metabolically active cells such as lymphoblasts, inflammatory cells, brown adipocytes, and malignant tumor cells.
It facilitates cell surface expression of monocarboxylate transporters and extracellular matrix metalloproteinases, regulates integrin functions, and plays roles in cell development, activation, fetal development, and retinal function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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