Thermo Fisher Scientific GNB3 Monoclonal Antibody (M1-1-1D5)
GNB3 단백질을 타겟하는 Thermo Fisher Scientific의 마우스 모노클로날 항체로, Western blot, ICC/IF, ELISA에 적합합니다. Human 반응성, IgG2a 아이소타입이며, PBS 버퍼에 보존제가 없는 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | M1-1-1D5 |
| Immunogen | GNB3 (AAH02454, 1–340 a.a) full-length recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MGEMEQLRQE AEQLKKQIAD ARKACAGVTL AELVSGLEVV GRVQMRTRRT LRGHLAKIYA MHWATDSKLL VSASQDGKLI VWDSYTTNKV HAIPLRSSWV MTCAYAPSGN FVACGGLDNM CSIYNLKSRE GNVKVSRELS AHTGYLSCCR FLDDNNIVTS SGDTTCALWD IETGQQKTVF VGHTGDCMSL AVSPDFNLFI SGACDASAKL WDVREGTCRQ TFTGHESDIN AICFFPNGEA ICTGSDDASC RLFDLRADQE LICFSHESII CSITSVAFSL SGRLLFAGYD DFNCNVWDSM KSERVGILSG HDNRVSCLGV TADGMAVATG SWDSFLKIWN
Target Information
Heterotrimeric guanine nucleotide-binding proteins encoded by this gene are associated with essential hypertension and obesity. This polymorphism is linked to the occurrence of the splice variant GNB3-s, which exhibits increased activity. GNB3-s represents an example of alternative splicing caused by a nucleotide change outside of splice donor and acceptor sites. Additional splice variants may exist but have not been fully described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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