Thermo Fisher Scientific NSD2 Monoclonal Antibody (CL1063)
Human NSD2 단백질을 인식하는 CL1063 클론의 Mouse Monoclonal Antibody로, WB, IHC, ICC/IF에 적합합니다. Protein A로 정제된 액상형 항체이며, 1 mg/mL 농도. 연구용으로만 사용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 2–10 µg/mL | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CL1063 |
| Immunogen | Recombinant protein corresponding to Human NSD2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637236 |
Product Specific Information
Immunogen sequence:
SANGKTPSCE VNRECSVFLS KAQLSSSLQE GVMQKFNGHD ALPFIPADKL KDLTSRVFNG EPGAHDAKLR FESQEMKGIG TPPNTTPIKN GSPEIKLKIT KTYMNGKPLF ESSICGD
Highest antigen sequence identity to orthologs:
- Mouse: 91%
- Rat: 91%
Binds to an epitope located within the peptide sequence ALPFIPADKL as determined by overlapping synthetic peptides.
Target Information
This gene encodes a protein containing four domains found in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously during early development.
Wolf-Hirschhorn syndrome (WHS) is associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and is also involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas.
Alternative splicing results in multiple transcript variants encoding different isoforms, with some being nonsense-mediated mRNA decay candidates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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