Thermo Fisher Scientific ELAC2 Polyclonal Antibody
ELAC2 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot에 적합합니다. 인간 ELAC2의 C-말단 펩타이드(aa 439-488)를 면역원으로 제작되었으며, 고순도 친화 크로마토그래피 정제 제품입니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific ELAC2 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1 µg/mL
Publications: - [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human ELAC2 (aa 439–488) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2605791 |
Product Specific Information
- Peptide sequence: ITCNPEEFIV EALQLPNFQQ SVQEYRRSAQ DGPAPAEKRS QYPEIIFLGT
- Sequence homology:
- Dog: 100%
- Human: 100%
- Mouse: 83%
- Rat: 83%
Target Information
ELAC2 encodes a protein with a C-terminal domain possessing tRNA 3′ processing endoribonuclease activity, responsible for removing the 3′ trailer from precursor tRNAs.
It interacts with activated Smad2 and its nuclear partner forkhead box H1 (FAST-1). Reduced expression can suppress TGF-β–induced growth arrest.
Mutations in ELAC2 are associated with increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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