Thermo Fisher Scientific ACSL5 Polyclonal Antibody, MaxPab

Thermo Fisher Scientific ACSL5 Polyclonal Antibody, MaxPab

Applications

• Western Blot (WB)

Tested Dilution

• 1–5 µg/mL

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MDALKPPCLW RNHERGKKDR DSCGRKNSEP GSPHSLEALR DAAPSQGLNF LLLFTKMLFI FNFLFSPLPT PALICILTFG AAIFLWLITR PQPVLPLLDL NNQSVGIEGG ARKGVSQKNN DLTSCCFSDA KTMYEVFQRG LAVSDNGPCL GYRKPNQPYR WLSYKQVSDR AEYLGSCLLH KGYKSSPDQF VGIFAQNRPE WIISELACYT YSMVAVPLYD TLGPEAIVHI VNKADIAMVI CDTPQKALVL IGNVEKGFTP SLKVIILMDP FDDDLKQRGE KSGIEILSLY DAENLGKEHF RKPVPPSPED LSVICFTSGT TGDPKGAMIT HQNIVSNAAA FLKCVEHAYE PTPDDVAISY LPLAHMFERI VQAVVYSCGA RVGFFQGDIR LLADDMKTLK PTLFPAVPRL LNRIYDKVQN EAKTPLKKFL LKLAVSSKFK ELQKGIIRHD SFWDKLIFAK IQDSLGGRVR VIVTGAAPMS TSVMTFFRAA MGCQVYEAYG QTECTGGCTF TLPGDWTSGH VGVPLACNYV KLEDVADMNY FTVNNEGEVC IKGTNVFKGY LKDPEKTQEA LDSDGWLHTG DIGRWLPNGT LKIIDRKKNI FKLAQGEYIA PEKIENIYNR SQPVLQIFVH GESLRSSLVG VVVPDTDVLP SFAAKLGVKG SFEELCQNQV VREAILEDLQ KIGKESGLKT FEQVKAIFLH PEPFSIENGL LTPTLKAKRG ELSKYFRTQI DSLYEHIQD

Target Information

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family.
Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation.
This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas.
This gene functions in mediating fatty acid-induced glioma cell growth.
Three transcript variants encoding two different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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