
Thermo Fisher Scientific PYDC1 Monoclonal Antibody (OTI7A2), TrueMAB
인간 PYDC1 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot에 적합합니다. 비결합형 형태로 제공되며, 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용되며, -20°C에서 보관합니다.
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Thermo Fisher Scientific PYDC1 Monoclonal Antibody (OTI7A2), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7A2 |
| Immunogen | Full length human recombinant protein of human PYDC1 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
ASC2 associates with PYCARD/ASC and modulates its ability to collaborate with MEFV/pyrin and NLRP3/cryopyrin in NF-kappa-B and pro-caspase-1 activation.
It suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes, and inhibits NF-kappa-B activation by cytokines and LPS.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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