Thermo Fisher Scientific PYDC1 Monoclonal Antibody (OTI2G7), TrueMAB
인간 PYDC1 단백질을 인식하는 마우스 단클론 항체. Western blot 등에 적합하며 TrueMAB 형식으로 제공. 동결건조 형태로 보존 안정성이 높고, 재구성 후 1 mg/mL 농도로 사용 가능. 연구용으로 NF-κB 신호 조절 관련 연구에 활용.
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- pk
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Applications
- Western Blot (WB)
Tested Dilution
- 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2G7 |
| Immunogen | Full length human recombinant protein of human PYDC1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional round of desalting.
Recommended desalting product: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
ASC2 associates with PYCARD/ASC and modulates its ability to collaborate with MEFV/pyrin and NLRP3/cryopyrin in NF-κB and pro-caspase-1 activation.
It suppresses kinase activity of NF-κB inhibitor kinase (IKK) complex, expression of NF-κB inducible genes, and inhibits NF-κB activation by cytokines and LPS.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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