Thermo Fisher Scientific Adipophilin/Perilipin-2 (Marker of Lipid Accumulation) Monoclonal Antibody (ADFP/1494)
Adipophilin/Perilipin-2 단백질을 표적하는 단클론 항체로, 지방 축적 마커 연구에 적합. 인간 시료 반응성, IHC 및 ELISA에 사용 가능. 고순도 Protein A/G 정제, 액상 형태로 4°C 보관. 연구용 전용 제품.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, lambda |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ADFP/1494 |
| Immunogen | Recombinant fragment (around aa 249–376) of human Adipophilin (ADFP) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Milk lipid globules from humans, cows, and rats contain a protein identified as adipocyte differentiation-related protein (ADFP). It is associated with the globule surface membrane material. This protein, previously believed to be specific to adipocytes, is a major constituent of the globule surface and is present in a detergent-insoluble complex that contains butyrophilin and xanthine oxidase.
ADFP (Adipophilin) is found in a wide range of cultured cell lines, including fibroblasts, endothelial, and epithelial cells. In tissues, expression of adipophilin is restricted to specific cell types such as lactating mammary epithelial cells, adrenal cortex cells, Sertoli and Leydig cells of the male reproductive system, and hepatocytes showing steatosis in alcoholic liver cirrhosis.
ADFP may serve as a marker for identifying specialized differentiated cells containing lipid droplets and for diseases associated with fat-accumulating cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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