Thermo Fisher Scientific 5HT2B R Polyclonal Antibody
5HT2B 수용체를 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC에 적합. 합성 펩타이드(aa 440-481)를 면역원으로 사용. 동결건조 형태이며 보존제 무첨가. 연구용으로 심장 발달 및 세로토닌 신호 연구에 활용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 440–481 of human 5HT2B receptor conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: 5HT2B receptor.
Target Information
HTR2B is a G-protein coupled receptor for 5-hydroxytryptamine (serotonin). It acts as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding induces conformational changes that activate G-protein signaling, modulating downstream effectors.
HTR2B also contributes to pain perception, behavioral regulation, and normal proliferation of embryonic cardiac myocytes, essential for heart development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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