Thermo Fisher Scientific ABCB8 Polyclonal Antibody
ABCB8 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF, ELISA에 적합합니다. 인간, 마우스, 랫트 반응성이 있으며, 고순도 친화성 정제 및 안정적 PBS/glycerol buffer로 제공됩니다. 연구용으로만 사용 가능합니다.
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- PA5120826
- 판매단위
- pk
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Thermo Fisher Scientific ABCB8 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 469–718 of human ABCB8 (NP_009119.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.37 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914398 |
Product Specific Information
- Positive test controls include: MCF7, Jurkat, HepG2, HeLa, Mouse heart, Mouse skin, Mouse kidney, Rat heart.
- Target locations: Mitochondrion inner membrane, Multi-pass membrane protein.
Immunogen sequence:
GFEVLKDFTL TLPPGKIVAL VGQSGGGKTT VASLLERFYD PTAGVVMLDG RDLRTLDPSW LRGQVVGFIS QEPVLFGTTI MENIRFGKLE ASDEEVYTAA REANAHEFIT SFPEGYNTVV GERGTTLSGG QKQRLAIARA LIKQPTVLIL DEATSALDAE SERVVQEALD RASAGRTVLV IAHRLSTVRG AHCIVVMADG RVWEAGTHEE LLKKGGLYAE LIRRQALDAP RTAAPPPKKP EGPRSHQHKS
Target Information
This nuclear gene encodes a multi-pass membrane protein targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function in mouse disrupts iron homeostasis between mitochondria and cytosol. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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