Thermo Fisher Scientific CERKL Polyclonal Antibody
Human CERKL 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 검증 완료. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 0.1 mg/mL 농도로 PBS 및 글리세롤 버퍼에 보존. 시각세포 관련 단백질 연구용으로 적합.
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Thermo Fisher Scientific CERKL Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CERKL. Recombinant protein control fragment (Product #RP-96221). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2639709 |
Product Specific Information
Immunogen sequence:
IARNTSRPEF IKHLKRYASV KNQFNFPFVE TYTVEEVKVH PRNNTGGYNP EEEEDETASE NCFPWNVDGD LMEVASEVHI RLHPRLISLY GGSMEEMI
Highest antigen sequence identity to the following orthologs:
- Mouse: 73%
- Rat: 73%
Target Information
This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. It encodes a protein with ceramide kinase-like domains, but the protein does not phosphorylate ceramide and its target substrate is unknown. It may act as a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing results in multiple transcript variants encoding different isoforms and non-coding transcripts.
[Provided by RefSeq, May 2010]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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