Thermo Fisher Scientific RHD Polyclonal Antibody
RHD 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 등 연구용에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며, 항원 특이적 친화 크로마토그래피로 정제되었습니다. 고순도(>95%)의 비결합형 액상 항체로 안정적인 장기 보관이 가능합니다.
- 카탈로그번호
- PA575922
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific RHD Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:1,000
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 168–213 of Human RHD |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2719650 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
The Rhesus (Rh) blood group system is one of the most complex and important systems in humans. Two highly homologous genes, RHD and RHCE (collectively referred to as RH30 or RHCED), encode the antigens of the Rh blood group system. These genes map to human chromosomal position 1p34.1–1p36.
The RHD gene, often deleted in a large portion of the population, encodes the potent D antigen, a major blood group immunogen. Rh incompatibility between maternal and fetal blood types can result in hemolytic disease of the newborn (HDN), which may lead to fetal death. The RHCE gene exists in four allelic forms, determining expression of Ce, ce, cE, or CE antigen combinations.
RHCED antigens are integral membrane proteins with 12 transmembrane helices that maintain erythrocyte membrane integrity. Proper presentation of Rh antigenic activity requires a complex formation between RHCED antigens and RHAG (RH50).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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