Thermo Fisher Scientific Chimaerin beta 2 Polyclonal Antibody, Biotin
Chimaerin beta 2 단백질을 인식하는 Biotin 결합 폴리클로날 항체. Western blot, IHC, ELISA, IP에 적합. Human, Mouse, Rat 반응성. Rabbit 유래 IgG 항체로, Affinity chromatography로 정제. -20°C 보관.
- 카탈로그번호
- CHIM2-BIOTIN
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 150–180 on beta 2-chimaerin protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene is a member of the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain, and an SH2 domain. It has GTPase-activating activity regulated by phospholipid binding, and binding of diacylglycerol (DAG) induces translocation from the cytosol to the Golgi membrane. The protein is involved in smooth muscle cell proliferation and migration. Decreased expression is associated with high-grade gliomas and breast tumors, while increased expression is linked to lymphomas. Mutations have been associated with schizophrenia in men. Alternate splice variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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