Thermo Fisher Scientific Chimaerin beta 2 Polyclonal Antibody, FITC
Chimaerin beta 2 단백질을 인식하는 FITC 결합 폴리클로날 항체로, WB, IHC, ELISA, IP 등에 사용 가능. 인간, 생쥐, 랫트 반응성. 고순도 친화 크로마토그래피 정제 제품으로 형광 검출에 적합. 연구용 전용.
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Thermo Fisher Scientific Chimaerin beta 2 Polyclonal Antibody, FITC
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 150–180 on beta 2-chimaerin protein |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene belongs to the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain, and an SH2 domain. It exhibits GTPase-activating protein activity regulated by phospholipid binding. Diacylglycerol (DAG) binding induces translocation of the protein from the cytosol to the Golgi apparatus membrane. The protein is involved in the proliferation and migration of smooth muscle cells. Decreased expression is associated with high-grade gliomas and breast tumors, while increased expression is linked to lymphomas. Mutations have been associated with schizophrenia in men. Alternate splice variants encoding different isoforms have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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