Thermo Fisher Scientific BMP-2 Recombinant Rabbit Monoclonal Antibody (110)
Recombinant rabbit monoclonal antibody targeting Human BMP-2. High specificity and sensitivity with consistent lot performance. Suitable for ICC/IF applications. Preservative-free formulation with Protein A purification. For research use only.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:20–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rhesus monkey, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 110 |
| Immunogen | Recombinant Human BMP-2 protein (Gln283–Arg396) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2784988 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned, and individual clones are screened for optimal performance.
Advantages of recombinant rabbit monoclonal antibodies:
- Superior specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity to diverse targets
This antibody has specificity for Human BMP-2.
Target Information
Bone Morphogenic Proteins (BMPs) are members of the TGF-beta superfamily involved in bone and cartilage formation. Mature BMPs are 30–38 kDa proteins with a TGF-beta-like cysteine knot structure. BMPs stimulate production of bone matrix proteins, influence stromal and osteoclast cell proliferation, and play roles in development, apoptosis, and morphogenesis. They function via binding to type II receptors, which recruit type I receptors to activate the Smad signaling pathway.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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