Thermo Fisher Scientific G6PD Monoclonal Antibody (3H5)

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000

ELISA

• Tested Dilution: 10 µg/mL

Product Specifications

Product Specific Information

Protein sequence (partial):
TKKPGMFFNP EESELDLTYG NRYKNVKLPD AYERLILDVF CGSQMHFVRS DELREAWRIF TPLLHQIELE KPKPIPYIYG SRGPTEADEL MKRVGFQYEG TYKWVNPHKL

Target Information

This gene encodes glucose-6-phosphate dehydrogenase (G6PD), a cytosolic enzyme encoded by a housekeeping X-linked gene. Its main function is to produce NADPH, a key electron donor in defense against oxidative stress and in reductive biosynthetic reactions.
G6PD exhibits significant genetic diversity, with many variants arising from missense mutations, resulting in a wide range of enzyme activities and clinical outcomes.
Deficiency in G6PD can cause neonatal jaundice, acute hemolysis, or chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.