Thermo Fisher Scientific Carboxypeptidase A1/CPA1 Monoclonal Antibody (CPA1, 2712)
Thermo Fisher Scientific의 CPA1 단일클론 항체로, 사람 및 개 시료에서 반응. WB, IHC, Peptide Array 등 다양한 응용 가능. 단백질 A/G로 정제된 액상 형태이며, 보존제 없음. 연구용으로만 사용.
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Thermo Fisher Scientific Carboxypeptidase A1/CPA1 Monoclonal Antibody (CPA1, 2712)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Human |
| Host / Isotype | Mouse / IgG2c, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CPA1, 2712 |
| Immunogen | Recombinant full-length human CPA1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 min at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
CPA1 (Carboxypeptidase A1), also known as CPA, is a 419 amino acid secreted monomeric protein highly expressed in pancreatic tissue. It functions as a pancreatic exopeptidase using zinc as a cofactor to catalyze the release of C-terminal amino acids from proteins, playing a key role in protein digestion and degradation. CPA1 may also inhibit zymogen activation pathways. Abnormal CPA1 levels are associated with pancreatic cancer, suggesting a role in tumor progression or suppression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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