Thermo Fisher Scientific Carboxypeptidase A1/CPA1 Monoclonal Antibody (CPA1, 2712)
Carboxypeptidase A1(CPA1)을 인식하는 mouse monoclonal antibody로 Western blot, IHC(P) 등 다양한 응용에 적합. Human 및 Dog 시료 반응성. Protein A/G 정제, 4°C 보관, 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL | - |
| Peptide Array (Array) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human |
| Host / Isotype | Mouse / IgG2c, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CPA1, 2712 |
| Immunogen | Recombinant full-length human CPA1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): incubate antibody for 30 minutes at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
CPA1, also known as Carboxypeptidase A1, is a 419 amino acid secreted monomeric protein highly expressed in pancreatic tissue.
It functions as a pancreatic exopeptidase using zinc as a cofactor to catalyze the release of C-terminal amino acids from various proteins, playing a key role in protein digestion and degradation.
CPA1 may also be involved in zymogen inhibition, potentially blocking enzyme activation pathways.
Abnormal CPA1 levels are associated with pancreatic cancer, suggesting a role in tumor progression or suppression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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