Thermo Fisher Scientific Lactyl-Histone H4 (Lys5) Polyclonal Antibody
Thermo Fisher Scientific의 Lactyl-Histone H4 (Lys5) Polyclonal Antibody는 인간, 생쥐, 랫트에 반응하며 Western blot, ELISA, Dot blot에 적합합니다. 합성 lactylated peptide를 면역원으로 사용한 rabbit IgG 폴리클로날 항체로, 높은 특이성과 안정성을 제공합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
| Dot blot (DB) | 1:500–1:4,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic lactylated peptide around K5 of human Histone H4 (NP_0035391) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.51 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2901530 |
Product Specific Information
- Positive Samples: C6
- Immunogen sequence: GRGKG
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fiber in eukaryotes. Approximately 146 bp of DNA wraps around a nucleosome, an octamer composed of pairs of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through interaction with linker histone H1 to form higher-order chromatin structures.
This gene is intronless and encodes a replication-dependent histone H4 family member. Transcripts lack polyA tails and contain a palindromic termination element. Located in a histone cluster on chromosome 1, this gene represents the centromeric copy among duplicated histone genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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