Thermo Fisher Scientific CD299 (DC-SIGN/L) Monoclonal Antibody (8A1B3)
인간 CD299(CLEC4M/DC-SIGN/L) 단백질을 인식하는 Mouse IgG1 단클론 항체입니다. Western blot, Flow cytometry, ELISA 등 다양한 응용에 사용 가능하며, Protein G로 정제된 액상 형태로 제공됩니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 8A1B3 |
| Immunogen | Purified recombinant fragment of human CD299 (aa 237–399) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898391 |
Product Specific Information
This antibody has been tested in indirect ELISA.
Target Information
CLEC4M is a type II integral membrane protein that is 77% identical to CD209 antigen, a HIV gp120-binding protein. Like CD209, it efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, enhancing HIV-1 infection of T cells.
Western blots using two different antibodies against unique regions of this protein confirm the same apparent molecular weight.
This gene is mapped to chromosome 19p13.3, clustered with CD209 and CD23/FCER2 genes. Multiple alternatively spliced transcript variants have been identified, though the biological validity of some variants remains undetermined.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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