Thermo Fisher Scientific PAF Polyclonal Antibody
PAF 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, IP 등 다양한 실험에 사용 가능. 액상 형태이며 1 mg/mL 농도로 제공. 4°C에서 보관하며, DNA 복제 및 손상 복구 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:2,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 61 to 111 of human PCNA-Associated Factor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
Target Information
PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, allowing bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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